Route 66

Jackson Boulevard was the starting point for the original Route 66, which means you can drive into Chicago on the “Mother Road” from the Kennedy Expressway, Illinois Interstate 90/94. Exit Jackson east and look for Lou Mitchell’s on your right located near the intersection of Jackson and Jefferson. Route 66 was created in 1926, and when the signs went up on Jackson Boulevard, commuters found Lou Mitchell’s waiting for them. We’ve been feeding the hungry travelers with comfort food since 1923. Drop in and enjoy our famous breakfast and/or lunch.
 

Since Jackson Boulevard is now a one way street east to Michigan Avenue, you will need to return to the expressway by way of Adams Street, which runs west one way. Adams begins in front of The Art Institute of Chicago. A little farther west on Adams is the Willi's Tower (formally known as Sears Tower)